Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50047637
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50180653(CHEMBL3194617)
Affinity DataKd:  1.53E+4nMAssay Description:Binding affinity to wild-type His6-tagged human 15-LOX expressed in Escherichia coli Rosetta DE3 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50180654(CHEMBL3817975)
Affinity DataKd:  4.40E+3nMAssay Description:Binding affinity to wild-type His6-tagged human 15-LOX expressed in Escherichia coli Rosetta DE3 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50180652(CHEMBL3819527)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to wild-type His6-tagged human 15-LOX expressed in Escherichia coli Rosetta DE3 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50180652(CHEMBL3819527)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mPGES-1 (unknown origin) assessed as reduction in conversion of PGH2 to PGE2 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed