Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50046388
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109277(CHEMBL3601686)
Affinity DataEC50:  423nMAssay Description:Modulation of P-gp in human MDA435/LCC6MDR cells assessed as reversal of paclitaxel resistanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataEC50:  446nMAssay Description:Modulation of P-gp in human MDA435/LCC6MDR cells assessed as reversal of paclitaxel resistanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109277(CHEMBL3601686)
Affinity DataIC50: 3.5nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109278(CHEMBL3601685)
Affinity DataIC50: 6.5nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109344(CHEMBL3601682)
Affinity DataIC50: 11nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109279(CHEMBL3601684)
Affinity DataIC50: 14nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109314(CHEMBL3601683)
Affinity DataIC50: 25nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109274(CHEMBL3601689)
Affinity DataIC50: 26nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109275(CHEMBL3601688)
Affinity DataIC50: 58nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109276(CHEMBL3601687)
Affinity DataIC50: 126nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109273(CHEMBL3601690)
Affinity DataIC50: 136nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed