Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50046443
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13216BDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 2nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112617BDBM50112617(CHEMBL3608786)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112628BDBM50112628(CHEMBL3608789)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112631BDBM50112631(CHEMBL3608790)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112618BDBM50112618(CHEMBL3608787)
Affinity DataIC50: 6nMAssay Description:Inhibition of DDR1 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112634BDBM50112634(CHEMBL3608791)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112618BDBM50112618(CHEMBL3608787)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112615BDBM50112615(CHEMBL3608785)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112617BDBM50112617(CHEMBL3608786)
Affinity DataEC50:  8.70nMAssay Description:Inhibition of collagen I-induced DDR2 (unknown origin) phosphorylation expressed in HEK293 cells after 16 hrs by mesoscale discovery assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112615BDBM50112615(CHEMBL3608785)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of c-Kit (unknown origin) using biotinylated HER2 peptide as substrate by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112617BDBM50112617(CHEMBL3608786)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Kit (unknown origin) using biotinylated HER2 peptide as substrate by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112628BDBM50112628(CHEMBL3608789)
Affinity DataIC50: 140nMAssay Description:Inhibition of c-Kit (unknown origin) using biotinylated HER2 peptide as substrate by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112613BDBM50112613(CHEMBL3608784)
Affinity DataIC50: 150nMAssay Description:Inhibition of DDR1 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112634BDBM50112634(CHEMBL3608791)
Affinity DataIC50: 160nMAssay Description:Inhibition of c-Kit (unknown origin) using biotinylated HER2 peptide as substrate by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112613BDBM50112613(CHEMBL3608784)
Affinity DataIC50: 180nMAssay Description:Inhibition of c-Kit (unknown origin) using biotinylated HER2 peptide as substrate by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112613BDBM50112613(CHEMBL3608784)
Affinity DataIC50: 280nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112618BDBM50112618(CHEMBL3608787)
Affinity DataIC50: 310nMAssay Description:Inhibition of c-Kit (unknown origin) using biotinylated HER2 peptide as substrate by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112624BDBM50112624(CHEMBL3608788)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of DDR2 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112624BDBM50112624(CHEMBL3608788)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of DDR1 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112637BDBM50112637(CHEMBL1299308)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DDR1 (unknown origin) after 1 hr by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)