Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50049056
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233644(CHEMBL4079989)
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233655(CHEMBL4101864)
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233653(CHEMBL4095573)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233654(CHEMBL4087347)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50063962(CHEMBL3402584)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233665(CHEMBL4103325)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233652(CHEMBL4075160)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233656(CHEMBL4083867)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233651(CHEMBL4085393)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233664(CHEMBL4105206)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233661(CHEMBL4094133)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233654(CHEMBL4087347)
Affinity DataIC50: 12nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233653(CHEMBL4095573)
Affinity DataIC50: 14nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233664(CHEMBL4105206)
Affinity DataIC50: 16nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233659(CHEMBL4086354)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233656(CHEMBL4083867)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233647(CHEMBL4073491)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50063962(CHEMBL3402584)
Affinity DataIC50: 22nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233651(CHEMBL4085393)
Affinity DataIC50: 27nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233648(CHEMBL4093393)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)
Affinity DataIC50: 27nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233655(CHEMBL4101864)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233644(CHEMBL4079989)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233647(CHEMBL4073491)
Affinity DataIC50: 32nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233645(CHEMBL4097010)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233660(CHEMBL4064893)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233649(CHEMBL4081221)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233652(CHEMBL4075160)
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233660(CHEMBL4064893)
Affinity DataIC50: 52nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233648(CHEMBL4093393)
Affinity DataIC50: 56nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233657(CHEMBL4063859)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233659(CHEMBL4086354)
Affinity DataIC50: 69nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233658(CHEMBL4091642)
Affinity DataIC50: 69nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233658(CHEMBL4091642)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233645(CHEMBL4097010)
Affinity DataIC50: 93nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233661(CHEMBL4094133)
Affinity DataIC50: 94nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233649(CHEMBL4081221)
Affinity DataIC50: 110nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233662(CHEMBL4065778)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233657(CHEMBL4063859)
Affinity DataIC50: 196nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233663(CHEMBL4105470)
Affinity DataIC50: 213nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233650(CHEMBL4070603)
Affinity DataIC50: 350nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233663(CHEMBL4105470)
Affinity DataIC50: 395nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233665(CHEMBL4103325)
Affinity DataIC50: 410nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233650(CHEMBL4070603)
Affinity DataIC50: 562nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233662(CHEMBL4065778)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233646(CHEMBL4087870)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus using biotin labeled peptide substrate after 1 hr by HRTF kinase/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50233646(CHEMBL4087870)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of BTK in human Ramos cells assessed as inhibition of anti human IgM-induced calcium influx preincubated for 20 mins in dark followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed