Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50006279
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 22nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin deoxyuridine triphosphate (biotin-dUTP) incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50498427(CHEMBL3593877)
Affinity DataIC50: 473nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin deoxyuridine triphosphate (biotin-dUTP) incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 807nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin deoxyuridine triphosphate (biotin-dUTP) incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50498428(CHEMBL3593248)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin deoxyuridine triphosphate (biotin-dUTP) incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50498429(CHEMBL3593512)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin deoxyuridine triphosphate (biotin-dUTP) incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed