Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 6789
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152604(1-[4-(2,6-dimethylphenyl)but-1-en-2-yl]-3,5-dimeth...)
Affinity DataIC50: 13nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM50087267((S)-4-(2-(N-methylisoquinoline-5-sulfonamido)-3-ox...)
Affinity DataIC50: 158nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152611(N'-(2-Chloro-7H-purin-6-yl)-3,5-dimethyladaman...)
Affinity DataIC50: 176nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152605(3,5-Dimethyl-N'-(quinolin-4-yl)adamantane-1-ca...)
Affinity DataIC50: 726nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152608(N'-(8-Chloroquinoline-4-yl)-3,5-dimethyladaman...)
Affinity DataIC50: 1.10E+3nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152610(3,5-Dimethyl-N'-(7H-purin-6-yl)adamantane-1-ca...)
Affinity DataIC50: 2.88E+3nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152607(3,5-Dimethyl-N'-(quinolin-2-yl)adamantane-1-ca...)
Affinity DataIC50: 2.90E+3nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152606(3,5-Dimethyl-N'-(quinolin-3-yl)adamantane-1-ca...)
Affinity DataIC50: 3.70E+3nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

LigandPNGBDBM152609(3,5-Dimethyl-N'-(quinazolin-4-yl)adamantane-1-...)
Affinity DataIC50: 5.50E+3nMpH: 7.4Assay Description:hP2X7-expressing HEK 293 cells were re-suspended at 2.5 × 10^6 cells/mL in assay buffer composed of 10 mM HEPES, 5 mM N-methyl-D-glutamine, 5.6 mM KC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed