Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50046163
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant BtkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant ALK2 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant TNK2 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant LIMK1 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataEC50:  28nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant BmxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant BlkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant FgrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase FRK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant FrkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant LynBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant TecMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant LynAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097394(CHEMBL3586446)
Affinity DataEC50:  92nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 99nMAssay Description:Inhibition of human recombinant HckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant ItkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 412nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097394(CHEMBL3586446)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097398(CHEMBL449216 | HTS-9026)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097395(CHEMBL3586445)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097394(CHEMBL3586446)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097397(CHEMBL3586443)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataEC50:  2.86E+4nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097398(CHEMBL449216 | HTS-9026)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097397(CHEMBL3586443)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097397(CHEMBL3586443)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097395(CHEMBL3586445)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed