Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50046110
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50095120(CHEMBL3589752)
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)