Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50045989
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089805BDBM50089805(CHEMBL3577590)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089806BDBM50089806(CHEMBL3577591)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089824BDBM50089824(CHEMBL3577592)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089803BDBM50089803(CHEMBL3577589)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089804BDBM50089804(CHEMBL3576878)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089831BDBM50089831(CHEMBL3577593)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089802BDBM50089802(CHEMBL3577588)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089785BDBM50089785(CHEMBL3577579)
Affinity DataIC50: 5.20E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089843BDBM50089843(CHEMBL3577594)
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089801BDBM50089801(CHEMBL3577587)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089800BDBM50089800(CHEMBL3577586)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089798BDBM50089798(CHEMBL3577584)
Affinity DataIC50: 2.25E+4nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089799BDBM50089799(CHEMBL3577585)
Affinity DataIC50: 2.48E+4nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089796BDBM50089796(CHEMBL3577583)
Affinity DataIC50: 4.89E+4nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089784BDBM50089784(CHEMBL3577578)
Affinity DataIC50: 7.62E+4nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089783BDBM50089783(CHEMBL3577577)
Affinity DataIC50: 1.06E+5nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089795BDBM50089795(CHEMBL3577582)
Affinity DataIC50: 1.18E+5nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089793BDBM50089793(CHEMBL3577581)
Affinity DataIC50: 1.44E+5nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
National Institute of Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089792BDBM50089792(CHEMBL3577580)
Affinity DataIC50: 2.43E+5nMAssay Description:Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diamino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed