Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50046017
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as whole cell current by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: 932nMAssay Description:Inhibition of human recombinant CYP3A4 using midazolam as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using testosterone as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using testosterone as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of human recombinant CYP3A4 using midazolam as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: 8.11E+3nMAssay Description:Inhibition of human recombinant CYP2C19 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: 8.54E+3nMAssay Description:Inhibition of human recombinant CYP2C9 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of human recombinant CYP2C19 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as whole cell current by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP2D6 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP2D6 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP1A2 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091324(CHEMBL3582240)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP2C9 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50091323(CHEMBL3582243)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP1A2 after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed