Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50046079
LigandPNGBDBM50093792(CHEMBL3585954)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50093790(CHEMBL3585956)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50093791(CHEMBL3585955)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50093794(CHEMBL3585953)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50093900(CHEMBL3585946)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50029064(CHEMBL3343259)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using rosiglitazone as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50029064(CHEMBL3343259)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50093788(CHEMBL3585957)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50029064(CHEMBL3343259)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-MS/MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50093798(CHEMBL3585951)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50029064(CHEMBL3343259)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-MS/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50029064(CHEMBL3343259)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-MS/M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using rosiglitazone as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-MS/M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-MS/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-MS/MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as susbtrate incubated for 30 mins prior to substrate addition for 10 mins by LC-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataKi:  0.440nMAssay Description:Binding affinity to human OX2R expressed in HEK-293 cells assessed as inhibition of orexin A-induced calcium accumulation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093788(CHEMBL3585957)
Affinity DataKi:  2nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093815(CHEMBL3585948)
Affinity DataKi:  2nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093795(CHEMBL3585952)
Affinity DataKi:  3nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataKi:  3nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093791(CHEMBL3585955)
Affinity DataKi:  3nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093798(CHEMBL3585951)
Affinity DataKi:  4nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093790(CHEMBL3585956)
Affinity DataKi:  4nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093788(CHEMBL3585957)
Affinity DataKi:  4nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50029064(CHEMBL3343259)
Affinity DataKi:  5nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to human OX1R expressed in HEK-293 cells assessed as inhibition of orexin A-induced calcium accumulation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093793(E-2006 | Lemborexant)
Affinity DataKi:  6nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093795(CHEMBL3585952)
Affinity DataKi:  6nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093798(CHEMBL3585951)
Affinity DataKi:  6nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093791(CHEMBL3585955)
Affinity DataKi:  7nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50094022(CHEMBL3585940)
Affinity DataKi:  7nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093900(CHEMBL3585946)
Affinity DataKi:  7nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50094039(CHEMBL3585938)
Affinity DataKi:  8nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093792(CHEMBL3585954)
Affinity DataKi:  8nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50094006(CHEMBL3585942)
Affinity DataKi:  9nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093780(CHEMBL3585936)
Affinity DataKi:  10nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093790(CHEMBL3585956)
Affinity DataKi:  14nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093794(CHEMBL3585953)
Affinity DataKi:  17nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50094007(CHEMBL3585941)
Affinity DataKi:  21nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093800(CHEMBL3585950)
Affinity DataKi:  29nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093801(CHEMBL3585949)
Affinity DataKi:  34nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093792(CHEMBL3585954)
Affinity DataKi:  39nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093815(CHEMBL3585948)
Affinity DataKi:  39nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50094006(CHEMBL3585942)
Affinity DataKi:  43nMAssay Description:Binding affinity to human OX1R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50094038(CHEMBL3585939)
Affinity DataKi:  49nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093976(CHEMBL3585944)
Affinity DataKi:  50nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50093897(CHEMBL3585947)
Affinity DataKi:  56nMAssay Description:Binding affinity to human OX2R by radioligand displacement binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
Displayed 1 to 50 (of 74 total ) | Next | Last >>
Jump to: