Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50045569
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 650nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068356(CHEMBL3402334)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068355(CHEMBL3402332)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068351(CHEMBL3402317)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.96E+4nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068356(CHEMBL3402334)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068351(CHEMBL3402317)
Affinity DataIC50: 6.47E+4nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068354(CHEMBL3402326)
Affinity DataIC50: 6.82E+4nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068352(CHEMBL3402318)
Affinity DataIC50: 7.96E+4nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068354(CHEMBL3402326)
Affinity DataIC50: 8.56E+4nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068353(CHEMBL3402325)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068355(CHEMBL3402332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068352(CHEMBL3402318)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068353(CHEMBL3402325)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.13E+5nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed