Compile Data Set for Download or QSAR
Report error Found 275 Enz. Inhib. hit(s) with all data for entry = 50045549
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067514BDBM50067514(CHEMBL3401978)
Affinity DataKi:  23nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067515BDBM50067515(CHEMBL3401979)
Affinity DataKi:  60nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  66nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067540BDBM50067540(CHEMBL3401990)
Affinity DataKi:  77nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067533BDBM50067533(CHEMBL3401984)
Affinity DataKi:  78nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067531BDBM50067531(CHEMBL3401983)
Affinity DataKi:  85nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067513BDBM50067513(CHEMBL3401977)
Affinity DataKi:  120nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  150nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067533BDBM50067533(CHEMBL3401984)
Affinity DataKi:  160nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067514BDBM50067514(CHEMBL3401978)
Affinity DataKi:  180nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067515BDBM50067515(CHEMBL3401979)
Affinity DataKi:  200nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067514BDBM50067514(CHEMBL3401978)
Affinity DataKi:  210nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067535BDBM50067535(CHEMBL3401986)
Affinity DataKi:  230nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067533BDBM50067533(CHEMBL3401984)
Affinity DataKi:  230nMAssay Description:Inhibition of PKAa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  240nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067513BDBM50067513(CHEMBL3401977)
Affinity DataKi:  250nMAssay Description:Inhibition of ROCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067514BDBM50067514(CHEMBL3401978)
Affinity DataKi:  270nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  310nMAssay Description:Inhibition of ROCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067517BDBM50067517(CHEMBL3401980)
Affinity DataKi:  310nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067513BDBM50067513(CHEMBL3401977)
Affinity DataKi:  320nMAssay Description:Inhibition of PLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067533BDBM50067533(CHEMBL3401984)
Affinity DataKi:  390nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067513BDBM50067513(CHEMBL3401977)
Affinity DataKi:  400nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067531BDBM50067531(CHEMBL3401983)
Affinity DataKi:  490nMAssay Description:Inhibition of PKAa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067533BDBM50067533(CHEMBL3401984)
Affinity DataKi:  510nMAssay Description:Inhibition of PLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067515BDBM50067515(CHEMBL3401979)
Affinity DataKi:  590nMAssay Description:Inhibition of PKAa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067513BDBM50067513(CHEMBL3401977)
Affinity DataKi:  620nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067514BDBM50067514(CHEMBL3401978)
Affinity DataKi:  630nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067518BDBM50067518(CHEMBL3401981)
Affinity DataKi:  690nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067533BDBM50067533(CHEMBL3401984)
Affinity DataKi:  710nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067540BDBM50067540(CHEMBL3401990)
Affinity DataKi:  740nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067515BDBM50067515(CHEMBL3401979)
Affinity DataKi:  750nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  780nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067515BDBM50067515(CHEMBL3401979)
Affinity DataKi:  800nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067531BDBM50067531(CHEMBL3401983)
Affinity DataKi:  840nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067540BDBM50067540(CHEMBL3401990)
Affinity DataKi:  840nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067513BDBM50067513(CHEMBL3401977)
Affinity DataKi:  850nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067515BDBM50067515(CHEMBL3401979)
Affinity DataKi:  880nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067538BDBM50067538(CHEMBL3401988)
Affinity DataKi:  970nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  970nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067538BDBM50067538(CHEMBL3401988)
Affinity DataKi:  980nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1/2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067531BDBM50067531(CHEMBL3401983)
Affinity DataKi:  980nMAssay Description:Inhibition of ROCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of PLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067515BDBM50067515(CHEMBL3401979)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of PLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067514BDBM50067514(CHEMBL3401978)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of PLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067539BDBM50067539(CHEMBL3401989)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of GSK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067535BDBM50067535(CHEMBL3401986)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50067531BDBM50067531(CHEMBL3401983)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067542BDBM50067542(CHEMBL3401976)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067538BDBM50067538(CHEMBL3401988)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of PKAa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067537BDBM50067537(CHEMBL3401987)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details Article
PubMed
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