Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50045965
TargetHistone deacetylase 8(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089101(CHEMBL3577691)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089086(CHEMBL3577704)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089090(CHEMBL3577697)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089091(CHEMBL3577696)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 174nMAssay Description:Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089093(CHEMBL3577693)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089085(CHEMBL3577694)
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089088(CHEMBL3577699)
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089100(CHEMBL3577692)
Affinity DataIC50: 321nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089089(CHEMBL3577698)
Affinity DataIC50: 527nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089087(CHEMBL3577703)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Fujian University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50089092(CHEMBL3577695)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2016
Entry Details Article
PubMed