Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50045840
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316229(2-(1,2,3,4-tetrahydroisoquinolin-6-yl)-2H-indazole...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 2nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316225((R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316228(2-(4-(pyrrolidin-2-yl)phenyl)-2H-indazole-7-carbox...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50084625(CHEMBL1098298)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316244(2-(4-((dimethylamino)methyl)phenyl)-2H-indazole-7-...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50084624(CHEMBL3427055)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50306210(2-(4-((methylamino)methyl)phenyl)-2H-indazole-7-ca...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316227(2-(4-(piperidin-4-yl)phenyl)-2H-indazole-7-carboxa...)
Affinity DataIC50: 9nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316233(2-(4-(2-(methylamino)propan-2-yl)phenyl)-2H-indazo...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50306166(2-phenyl-2H-indazole-7-carboxamide | CHEMBL594298)
Affinity DataIC50: 24nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316246(2-phenylpyrazolo-[1,5-a]pyridine-7-carboxamide | C...)
Affinity DataIC50: 55nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316247(2-phenyl-2H-benzo[d][1,2,3]triazole-4-carboxamide ...)
Affinity DataIC50: 71nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50316245(2-phenyl[1,2,4]triazolo[1,5-a]pyridine-8-carboxami...)
Affinity DataIC50: 270nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)