Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50045511
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065665(CHEMBL3404004)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065667(CHEMBL3404002)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065666(CHEMBL3404003)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant renin in presence of plasma by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065661(CHEMBL3404001)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant renin in presence of plasma by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065661(CHEMBL3404001)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065678(CHEMBL3403990)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065680(CHEMBL3403988)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065664(CHEMBL3404005)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065681(CHEMBL3403987)
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065675(CHEMBL3403993)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065669(CHEMBL3403999)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065668(CHEMBL3404000)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065662(CHEMBL3403986)
Affinity DataIC50: 145nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065676(CHEMBL3403992)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065682(CHEMBL3403985)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065683(CHEMBL3403984)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065673(CHEMBL3403994)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065679(CHEMBL3403989)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065671(CHEMBL3403997)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065685(CHEMBL3403981)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-adrenoceptor 1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065677(CHEMBL3403991)
Affinity DataIC50: 550nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065663(CHEMBL3403982)
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065663(CHEMBL3403982)
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant renin in presence of plasma by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of alpha-adrenoceptor 2A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of alpha-adrenoceptor 2B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065662(CHEMBL3403986)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant renin in presence of plasma by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065670(CHEMBL3403998)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065684(CHEMBL3403983)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using 7-benzyl-4-trifluoromethylcoumarin as fluorometric substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065672(CHEMBL3403996)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human recombinant renin by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetGastricsin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of pepsin C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetPepsin A-5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of pepsin A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCathepsin E(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of cathepsin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50065660(CHEMBL3403995)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed