Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50045464
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 180nMAssay Description:Inhibition of SMYD2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 230nMAssay Description:Inhibition of EHMT1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of SUV39H1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063676(CHEMBL3397325)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of G9a (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of EZH1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of SETDB1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MLL (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063685(CHEMBL3397329)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of EZH1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063674(CHEMBL3397327)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of SUV39H1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SUV420H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063684(CHEMBL3397330)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of MLL (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063671(CHEMBL3397316)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063678(CHEMBL3397323)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063672(CHEMBL3397315)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063677(CHEMBL3397324)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EHMT1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SETD7 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of SUV39H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063683(CHEMBL3397331)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063680(CHEMBL3397319)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063673(CHEMBL3397328)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063675(CHEMBL3397326)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063679(CHEMBL3397320)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063682(CHEMBL3397317)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SMYD2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of G9a (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SETDB1 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV39H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SETD7 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063681(CHEMBL3397318)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed