Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50035805
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017484(CHEMBL282212 | 5,9-Diamino-2-methyl-4-oxo-nonanoic...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017477(CHEMBL27803 | 5-Amino-2,7-dimethyl-4-oxo-octanoic ...)
Affinity DataIC50: 4.00E+5nMAssay Description:Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017472(CHEMBL284714 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017479(CHEMBL28708 | 2-(5,9-Diamino-2-methyl-4-oxo-nonano...)
Affinity DataIC50: 5.00E+5nMAssay Description:Competitive inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017470(CHEMBL28777 | 5-Amino-2-benzyl-4-hydroxy-7-methyl-...)
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017476(CHEMBL28623 | 5,9-Diamino-2-benzyl-4-oxo-nonanoic ...)
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50405948(CHEMBL2114365)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017470(CHEMBL28777 | 5-Amino-2-benzyl-4-hydroxy-7-methyl-...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017476(CHEMBL28623 | 5,9-Diamino-2-benzyl-4-oxo-nonanoic ...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017484(CHEMBL282212 | 5,9-Diamino-2-methyl-4-oxo-nonanoic...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017480(CHEMBL281437 | 5-Amino-8-guanidino-2-(4-hydroxy-be...)
Affinity DataKi:  0.840nMAssay Description:Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017482(CHEMBL282583 | 5-Amino-2-benzyl-8-guanidino-4-oxo-...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetGastricsin(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017485(3-Hydroxy-6-methyl-4-[3-methyl-2-(3-methyl-butyryl...)
Affinity DataKi:  3nMAssay Description:Inhibition of enzyme pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetGastricsin(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017486(CHEMBL424222 | 2-(2-{4-Hydroxy-2,7-dimethyl-5-[3-m...)
Affinity DataKi:  3nMAssay Description:Inhibition of enzyme pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017476(CHEMBL28623 | 5,9-Diamino-2-benzyl-4-oxo-nonanoic ...)
Affinity DataKi:  4nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataKi:  14nMAssay Description:Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataKi:  20nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017478(CHEMBL28650 | Amastatin | Leu[1psi,CHOHCONH]ValVal...)
Affinity DataKi:  20nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50027141(1-(5-Benzoylamino-4-oxo-6-phenyl-hexanoyl)-pyrroli...)
Affinity DataKi:  100nMAssay Description:Compound was evaluated for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetGastricsin(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017481(CHEMBL28888 | 2-(2-{2,7-Dimethyl-5-[3-methyl-2-(3-...)
Affinity DataKi:  110nMAssay Description:Inhibition of enzyme pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50008434(CHEMBL140459 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataKi:  170nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017478(CHEMBL28650 | Amastatin | Leu[1psi,CHOHCONH]ValVal...)
Affinity DataKi:  220nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50405948(CHEMBL2114365)
Affinity DataKi:  770nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetRenin(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017487(CHEMBL264354 | D-His-Pro-Phe-His-Ile-Ile-Val-Tyr-O...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of enzyme reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017484(CHEMBL282212 | 5,9-Diamino-2-methyl-4-oxo-nonanoic...)
Affinity DataKi:  2.00E+3nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017479(CHEMBL28708 | 2-(5,9-Diamino-2-methyl-4-oxo-nonano...)
Affinity DataKi:  2.00E+3nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017479(CHEMBL28708 | 2-(5,9-Diamino-2-methyl-4-oxo-nonano...)
Affinity DataKi:  2.80E+3nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the KidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM23971(CHEMBL29292 | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017483(CHEMBL284228 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataKi:  8.30E+3nMAssay Description:Competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017479(CHEMBL28708 | 2-(5,9-Diamino-2-methyl-4-oxo-nonano...)
Affinity DataKi:  8.80E+3nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017483(CHEMBL284228 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataKi:  2.50E+4nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017483(CHEMBL284228 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataKi:  3.60E+4nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50008434(CHEMBL140459 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataKi:  5.70E+4nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50008434(CHEMBL140459 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataKi:  7.90E+4nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017473(CHEMBL27690 | 5-Amino-2,7-dimethyl-4-oxo-octanoic ...)
Affinity DataKi:  1.30E+5nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017477(CHEMBL27803 | 5-Amino-2,7-dimethyl-4-oxo-octanoic ...)
Affinity DataKi:  1.30E+5nMAssay Description:Competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017470(CHEMBL28777 | 5-Amino-2-benzyl-4-hydroxy-7-methyl-...)
Affinity DataKi:  1.70E+5nMAssay Description:Competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017479(CHEMBL28708 | 2-(5,9-Diamino-2-methyl-4-oxo-nonano...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50405948(CHEMBL2114365)
Affinity DataKi:  2.40E+5nMAssay Description:Competitive inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50008434(CHEMBL140459 | 5-Amino-2-benzyl-7-methyl-4-oxo-oct...)
Affinity DataKi:  2.60E+5nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017480(CHEMBL281437 | 5-Amino-8-guanidino-2-(4-hydroxy-be...)
Affinity DataKi: >2.97E+5nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017482(CHEMBL282583 | 5-Amino-2-benzyl-8-guanidino-4-oxo-...)
Affinity DataKi: >3.12E+5nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017477(CHEMBL27803 | 5-Amino-2,7-dimethyl-4-oxo-octanoic ...)
Affinity DataKi:  3.50E+5nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017473(CHEMBL27690 | 5-Amino-2,7-dimethyl-4-oxo-octanoic ...)
Affinity DataKi:  6.60E+5nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017473(CHEMBL27690 | 5-Amino-2,7-dimethyl-4-oxo-octanoic ...)
Affinity DataKi:  9.40E+5nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50017473(CHEMBL27690 | 5-Amino-2,7-dimethyl-4-oxo-octanoic ...)
Affinity DataKi:  1.10E+6nMAssay Description:Competitive inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 1/2A(Pig)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50228232(CHEMBL283817)
Affinity DataKi:  4.20E+6nMAssay Description:Inhibition of porcine pancreatic elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed