Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50045657
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073143(CHEMBL3407730)
Affinity DataIC50: 160nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073148(CHEMBL3407729)
Affinity DataIC50: 920nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50302275(4-((2-(4,6-dimorpholino-1,3,5-triazin-2-yl)hydrazo...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073146(CHEMBL3407721)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073148(CHEMBL3407729)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073145(CHEMBL3407718)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073143(CHEMBL3407730)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073147(CHEMBL2088442)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073145(CHEMBL3407718)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073144(CHEMBL3407717)
Affinity DataIC50: 4.62E+3nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50302275(4-((2-(4,6-dimorpholino-1,3,5-triazin-2-yl)hydrazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073144(CHEMBL3407717)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3K-alpha kinase (unknown origin) using ULight-4E-BP1 as substrate after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073146(CHEMBL3407721)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50073147(CHEMBL2088442)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mTOR kinase (unknown origin) using ULight-4E-BP1 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed