Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50045058
TargetRho-associated protein kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to human Rock2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to human LIMK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044006(CHEMBL3356431)
Affinity DataIC50: 1nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044086(CHEMBL3356064)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044012(CHEMBL3356424)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044010(CHEMBL3356426)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044003(CHEMBL3356430)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044087(CHEMBL3356063)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044011(CHEMBL3356425)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044009(CHEMBL3356427)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044007(CHEMBL3356429)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299618((S)-N-(3-(isopropylcarbamoyl)phenyl)-2-methyl-4-(5...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044005(CHEMBL3356432)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044083(CHEMBL3352853)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044017(CHEMBL3356419)
Affinity DataIC50: 26nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 32nMAssay Description:Inhibition of human LIMK1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 32nMAssay Description:Inhibition of human Rock2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 54nMAssay Description:Inhibition of human LIMK1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 69nMAssay Description:Inhibition of human Rock1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044013(CHEMBL3356423)
Affinity DataIC50: 110nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044005(CHEMBL3356432)
Affinity DataIC50: 134nMAssay Description:Inhibition of human LIMK1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044008(CHEMBL3356428)
Affinity DataIC50: 138nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044005(CHEMBL3356432)
Affinity DataIC50: 139nMAssay Description:Inhibition of human Rock1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044082(CHEMBL3356066)
Affinity DataIC50: 180nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044014(CHEMBL3356422)
Affinity DataIC50: 210nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044018(CHEMBL3356068)
Affinity DataIC50: 220nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044015(CHEMBL3356421)
Affinity DataIC50: 330nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Rock2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044006(CHEMBL3356431)
Affinity DataIC50: 514nMAssay Description:Inhibition of human Rock1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044085(CHEMBL3356065)
Affinity DataIC50: 660nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetLIM domain kinase 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044016(CHEMBL3356420)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human Rock1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50044003(CHEMBL3356430)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human Rock1 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed