Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 7016
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166634(7-[(4-Fluorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 0.890nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166642(7-[(4-Cyanobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 1.20nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166633(7-[(3-Fluorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 1.30nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166641(7-[(3-Cyanobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 3.10nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166637(7-[(3-Bromobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 3.30nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166638(7-[(4-Bromobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 3.5nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166643(7-{[3-(Trifluoromethyl)benzyl]oxy}-3,4-dihydronaph...)
Affinity DataIC50: 3.80nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166640(7-[(4-Methylbenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 3.80nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166635(7-[(3-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 4nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166636(7-[(4-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 4.10nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166630(7-(Benzyloxy)-3,4-dihydronaphthalen-1(2H)-one (4a))
Affinity DataIC50: 7.20nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166644(7-{[4-(Trifluoromethyl)benzyl]oxy}-3,4-dihydronaph...)
Affinity DataIC50: 7.70nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166642(7-[(4-Cyanobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 10nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166634(7-[(4-Fluorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 12nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166639(7-[(4-Iodobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)-...)
Affinity DataIC50: 20nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166632(7-(3-Phenylpropoxy)-3,4-dihydronaphthalen-1(2H)-on...)
Affinity DataIC50: 22nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166641(7-[(3-Cyanobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 26nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166636(7-[(4-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 33nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166638(7-[(4-Bromobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 34nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166631(7-(2-Phenylethoxy)-3,4-dihydronaphthalen-1(2H)-one...)
Affinity DataIC50: 47nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166633(7-[(3-Fluorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 129nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166635(7-[(3-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 161nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166639(7-[(4-Iodobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)-...)
Affinity DataIC50: 283nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166637(7-[(3-Bromobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)...)
Affinity DataIC50: 328nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166631(7-(2-Phenylethoxy)-3,4-dihydronaphthalen-1(2H)-one...)
Affinity DataIC50: 366nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166643(7-{[3-(Trifluoromethyl)benzyl]oxy}-3,4-dihydronaph...)
Affinity DataIC50: 375nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166630(7-(Benzyloxy)-3,4-dihydronaphthalen-1(2H)-one (4a))
Affinity DataIC50: 443nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166640(7-[(4-Methylbenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 741nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166632(7-(3-Phenylpropoxy)-3,4-dihydronaphthalen-1(2H)-on...)
Affinity DataIC50: 1.17E+3nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166644(7-{[4-(Trifluoromethyl)benzyl]oxy}-3,4-dihydronaph...)
Affinity DataIC50: 1.26E+3nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166645(7-Hydroxy-1-tetralone (5))
Affinity DataIC50: 3.94E+4nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166645(7-Hydroxy-1-tetralone (5))
Affinity DataIC50: 1.87E+5nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed