Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50046235
TargetCytochrome P450 3A4(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101586(CHEMBL3394868)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101586(CHEMBL3394868)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101586(CHEMBL3394868)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101586(CHEMBL3394868)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101586(CHEMBL3394868)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101586(CHEMBL3394868)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG channel by planar techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101586(CHEMBL3394868)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG channel by QPatch techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed