Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50045401
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060917(ON-01910 | Rigosertib)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060911(CHEMBL3394764)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060910(CHEMBL3394763)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060913(CHEMBL3394766)
Affinity DataIC50: 960nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060916(CHEMBL3394757)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060912(CHEMBL3394765)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060905(CHEMBL3394758)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060906(CHEMBL3394759)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM166686(2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-di...)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060909(CHEMBL3394762)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060915(CHEMBL3394768)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060908(CHEMBL3394761)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060907(CHEMBL3394760)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060914(CHEMBL3394767)
Affinity DataIC50: 5.71E+3nMAssay Description:Inhibition of recombinant Plk1 (unknown origin) preincubated for 30 mins before recombinant Cdc25C substrate addition by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM166686(2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-di...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant Plk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060911(CHEMBL3394764)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Plk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50060911(CHEMBL3394764)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Plk3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM166686(2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-di...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Plk3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed