Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50045768
TargetSubstance-P receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50101417([1-Dimethylaminomethyl-2-(1H-indol-3-yl)-1-(1-phen...)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50101416([2-(1H-Indol-3-yl)-1-methyl-1-(1-phenyl-ethylcarba...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at NK1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017376(1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM22874(CHEMBL914 | Allegra | 2-(4-{1-hydroxy-4-[4-(hydrox...)
Affinity DataIC50: 15nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]naloxone from MOR (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50017376(1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl...)
Affinity DataKi:  56nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50370478(Morphine 6-Glucuronide(Minor) | MORPHINE-6-GLUCURO...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]naloxone from MOR (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
LigandPNGBDBM22874(CHEMBL914 | Allegra | 2-(4-{1-hydroxy-4-[4-(hydrox...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed