Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50044979
TargetFibroblast growth factor receptor 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50039984(CHEMBL3358802)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) using peptide substrate GS2 assessed as ATP remaining by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50039985(CHEMBL3358803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3beta (unknown origin) using peptide substrate GS2 assessed as ATP remaining by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50039986(CHEMBL3358804)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GSK3beta (unknown origin) using peptide substrate GS2 assessed as ATP remaining by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed