Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50048815
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM29568([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
Affinity DataIC50: 0.600nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataIC50: 9.10nMAssay Description:Alpha-2 adrenergic receptor activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM31046(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Affinity DataIC50: 10nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM31046(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Affinity DataIC50: 10nMAssay Description:Alpha-2 adrenergic receptor activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228240(CHEMBL284056)
Affinity DataIC50: 41nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM29568([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
Affinity DataIC50: 140nMAssay Description:Alpha-2 adrenergic receptor activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 210nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50: 270nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50: 300nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228242(CHEMBL542812)
Affinity DataIC50: 380nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228244(CHEMBL553942)
Affinity DataIC50: 470nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228242(CHEMBL542812)
Affinity DataIC50: 480nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228237(CHEMBL554455)
Affinity DataIC50: 480nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228237(CHEMBL554455)
Affinity DataIC50: 500nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228241(CHEMBL540511)
Affinity DataIC50: 830nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228241(CHEMBL540511)
Affinity DataIC50: 1.00E+3nMAssay Description:Alpha-2-adrenolytic activity was assessed in vitro from the ability to inhibit norepinephrine binding to guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataIC50: 1.00E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228237(CHEMBL554455)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228244(CHEMBL553942)
Affinity DataIC50: 1.00E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50101815(CHEBI:7550 | Nicardipine)
Affinity DataIC50: 1.40E+3nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228240(CHEMBL284056)
Affinity DataIC50: 1.60E+3nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 1.90E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 1.90E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 1.90E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228239(CHEMBL2093965)
Affinity DataIC50: 2.00E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228243(CHEMBL542814)
Affinity DataIC50: 2.00E+3nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228241(CHEMBL540511)
Affinity DataIC50: 3.50E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50101815(CHEBI:7550 | Nicardipine)
Affinity DataIC50: 3.60E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228243(CHEMBL542814)
Affinity DataIC50: 3.90E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 4.00E+3nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 4.00E+3nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228240(CHEMBL284056)
Affinity DataIC50: 1.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50101815(CHEBI:7550 | Nicardipine)
Affinity DataIC50: 1.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228239(CHEMBL2093965)
Affinity DataIC50: 1.00E+4nMAssay Description:Alpha-2-adrenolytic activity was assessed in vitro from the ability to inhibit norepinephrine binding to guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228238(CHEMBL30911)
Affinity DataIC50: 1.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50101815(CHEBI:7550 | Nicardipine)
Affinity DataIC50: 1.00E+4nMAssay Description:Alpha-2-adrenolytic activity was assessed in vitro from the ability to inhibit norepinephrine binding to guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 1.60E+4nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
LigandPNGBDBM50228239(CHEMBL2093965)
Affinity DataIC50: 1.90E+4nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 3.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 3.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 3.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228237(CHEMBL554455)
Affinity DataIC50: 4.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228242(CHEMBL542812)
Affinity DataIC50: 7.00E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 7.50E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228236(CHEMBL3350238)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 1.00E+5nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed