Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50045596
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 0.25nMAssay Description:Agonist activity at mouse A3 adenosine receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 15 min...More data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human recombinant A3 adenosine receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production aft...More data for this Ligand-Target Pair
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 0.320nMAssay Description:Agonist activity at mouse A3 adenosine receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 15 min...More data for this Ligand-Target Pair
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Agonist activity at mouse A3 adenosine receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 15 min...More data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 0.420nMAssay Description:Agonist activity at human recombinant A3 adenosine receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production aft...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP1A2 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C9 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C19 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP3A4 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CYP2D6 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human microsomes preincubated for 5 mins before substrate addition measured after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human ERG by PDSP screeningMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human ERG by PDSP screeningMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human ERG by PDSP screeningMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human ERG by PDSP screeningMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.570nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.770nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.850nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant A3 adenosine receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair






















