Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50045594
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataKi:  0.880nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50300121(US8680132, MI- 219 | CHEMBL572933 | (2'R,3S,4'R,5'...)
Affinity DataKi:  24nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50: 90nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50069799(CHEMBL3407579 | US9187441, 7M)
Affinity DataKi:  130nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50392531(CHEMBL407632)
Affinity DataIC50: 140nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50069801(CHEMBL3407580)
Affinity DataKd:  800nMAssay Description:Binding affinity to human MDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  916nMAssay Description:Binding affinity to human MDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50069800(CHEMBL3407578)
Affinity DataKi:  8.46E+3nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed