Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 50046284
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103557(CHEMBL3358000)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103551(CHEMBL3358013)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103552(CHEMBL3358014)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103564(CHEMBL3218816)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103563(CHEMBL3357994)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103562(CHEMBL3357995)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103561(CHEMBL3357996)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103560(CHEMBL3357997)
Affinity DataEC50:  133nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103559(CHEMBL3357998)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103558(CHEMBL3357999)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103550(CHEMBL3358012)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103556(CHEMBL3358001)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103555(CHEMBL3358002)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103554(CHEMBL3358003)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103553(CHEMBL3358004)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103564(CHEMBL3218816)
Affinity DataEC50:  436nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103563(CHEMBL3357994)
Affinity DataEC50:  144nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103562(CHEMBL3357995)
Affinity DataEC50:  1.98E+3nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103560(CHEMBL3357997)
Affinity DataEC50:  297nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103544(CHEMBL3358005)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103552(CHEMBL3358014)
Affinity DataEC50:  60nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103551(CHEMBL3358013)
Affinity DataEC50:  160nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103550(CHEMBL3358012)
Affinity DataEC50:  80nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103549(CHEMBL3358011)
Affinity DataEC50:  28nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103548(CHEMBL3358010)
Affinity DataEC50:  140nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103547(CHEMBL3358009)
Affinity DataEC50:  389nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103546(CHEMBL3358008)
Affinity DataEC50:  492nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103545(CHEMBL3358007)
Affinity DataEC50:  106nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103543(CHEMBL3358006)
Affinity DataEC50:  68nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103559(CHEMBL3357998)
Affinity DataEC50:  319nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103561(CHEMBL3357996)
Affinity DataEC50:  72nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103544(CHEMBL3358005)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103543(CHEMBL3358006)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103545(CHEMBL3358007)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103546(CHEMBL3358008)
Affinity DataEC50:  91nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103547(CHEMBL3358009)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103548(CHEMBL3358010)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103549(CHEMBL3358011)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103558(CHEMBL3357999)
Affinity DataEC50:  216nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103557(CHEMBL3358000)
Affinity DataEC50:  58nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103556(CHEMBL3358001)
Affinity DataEC50:  249nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103555(CHEMBL3358002)
Affinity DataEC50:  42nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103554(CHEMBL3358003)
Affinity DataEC50:  976nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103553(CHEMBL3358004)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103543(CHEMBL3358006)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
LigandPNGBDBM50103544(CHEMBL3358005)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
LigandPNGBDBM50103561(CHEMBL3357996)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
LigandPNGBDBM50103557(CHEMBL3358000)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
LigandPNGBDBM50103562(CHEMBL3357995)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
LigandPNGBDBM50103563(CHEMBL3357994)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
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