Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50045340
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 49nMAssay Description:Inhibition of DHFR activity of Cryptosporidium hominis bifunctional dihydrofolate reductase-thymidylate synthase assessed as reduction in NADPH oxida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 380nMAssay Description:Inhibition of thymidylate synthase activity of Cryptosporidium hominis bifunctional dihydrofolate reductase-thymidylate synthase assessed as reductio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 640nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed