Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50045207
LigandPNGBDBM31596(substituted pyrazole, 13)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049925(CHEMBL3317682)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049931(CHEMBL3317688)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049930(CHEMBL3317687)
Affinity DataIC50: 42nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50334662(2-Methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049932(CHEMBL3317689)
Affinity DataIC50: 55nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049926(CHEMBL3317683)
Affinity DataIC50: 170nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049929(CHEMBL3317686)
Affinity DataIC50: 190nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049927(CHEMBL3317684)
Affinity DataIC50: 220nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049933(CHEMBL3317690)
Affinity DataIC50: 480nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049934(CHEMBL3317691)
Affinity DataIC50: 900nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049935(CHEMBL3317692)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50049928(CHEMBL3317685)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed