Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50044416
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataIC50: 1.35E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataIC50: 3.04E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM85332(MDMA, R(-))
Affinity DataIC50: 1.73E+5nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  630nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM85332(MDMA, R(-))
Affinity DataKi:  8.21E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataKi:  2.45E+4nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat cortex, striatum and cerebellum-dissected brain after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed