Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50045123
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045830(CHEMBL3314362)
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)
Affinity DataIC50: 70nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045838(CHEMBL3314358)
Affinity DataIC50: 110nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045842(CHEMBL3314354)
Affinity DataIC50: 130nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 240nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045834(CHEMBL3314361)
Affinity DataIC50: 460nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045837(CHEMBL3314359)
Affinity DataIC50: 500nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045846(CHEMBL3314350)
Affinity DataIC50: 570nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045836(CHEMBL3314360)
Affinity DataIC50: 710nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045830(CHEMBL3314362)
Affinity DataIC50: 880nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045830(CHEMBL3314362)
Affinity DataIC50: 880nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045845(CHEMBL3314351)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045840(CHEMBL3314356)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
LigandPNGBDBM50045833(CHEMBL3314349)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045841(CHEMBL3314355)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
LigandPNGBDBM50045833(CHEMBL3314349)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
LigandPNGBDBM50045830(CHEMBL3314362)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045844(CHEMBL3314353)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045830(CHEMBL3314362)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045830(CHEMBL3314362)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
LigandPNGBDBM50045830(CHEMBL3314362)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045839(CHEMBL3314357)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed