Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50043771
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM27497(2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...)
Affinity DataEC50:  20nMAssay Description:Inhibition of ARTD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50137381(2-{4-[(R)-Hydroxy-3-(S)-5-(6-amino-purin-9-yl)-4-h...)
Affinity DataIC50: 45nMAssay Description:Inhibition of ARTD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Bovine)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM27500(Phenanthridone | 5H-Phenanthridin-6-one (PTD) | 5H...)
Affinity DataIC50: 300nMAssay Description:Inhibition of calf thymus ARTD1 assessed as incorporation of [Ade-U-14C]-NAD+ after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Bovine)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50446131(CHEMBL3108871)
Affinity DataIC50: 450nMAssay Description:Inhibition of bovine ARTD1 assessed as incorporation of [adenine-2,8-3H]NAD after 1 hr by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human full-length recombinant ARTD1 assessed as incorporation of [32P]NAD+ by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)