Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50043680
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444576(CHEMBL3099705)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to C-terminal 6xHis-tagged Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444578(CHEMBL3099706)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to C-terminal 6xHis-tagged Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444582(CHEMBL3099715)
Affinity DataKd:  25nMAssay Description:Binding affinity to C-terminal 6xHis-tagged Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444582(CHEMBL3099715)
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444581(CHEMBL3099713)
Affinity DataIC50: 220nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444580(CHEMBL3099714)
Affinity DataIC50: 230nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444579(CHEMBL3099712)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444578(CHEMBL3099706)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444577(CHEMBL3099711)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444575(CHEMBL3099710)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444574(CHEMBL3099708)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444573(CHEMBL3099709)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDNA ligase(Staphylococcus aureus)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444572(CHEMBL3099707)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged full length recombinant Staphylococcus aureus DNA ligase (1 to 312) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed