Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50042103
TargetMitogen-activated protein kinase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15913(4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50: 37nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 131nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50: 190nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420399(CHEMBL2089253)
Affinity DataIC50: 228nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 231nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15926(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-phenyla...)
Affinity DataIC50: 260nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15912(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 350nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15912(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 529nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15913(4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 568nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420399(CHEMBL2089253)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420400(CHEMBL2089254)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420398(CHEMBL2089252)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target40S ribosomal protein S27(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15926(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-phenyla...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420398(CHEMBL2089252)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JNK1-mediated ATF2 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed