Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50040550
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086051(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086062(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396033(CHEMBL2169982)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50086056(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396034(TCMDC-139046 | CHEMBL586213)
Affinity DataIC50: 50nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396038(CHEMBL2169978)
Affinity DataIC50: 120nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396037(CHEMBL2169979)
Affinity DataIC50: 180nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396032(CHEMBL2169985)
Affinity DataIC50: 390nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396030(CHEMBL2169991)
Affinity DataIC50: 600nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396031(CHEMBL2169990)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396034(TCMDC-139046 | CHEMBL586213)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CYP2C9 using 7-methoxy-4-triflouromethylcoumarin-3-acetic acid as substrate incubated for 30 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396035(CHEMBL2169981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396034(TCMDC-139046 | CHEMBL586213)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human CYP2D6 using 4-methylaminomethyl-7-methoxycoumarin as substrate incubated for 30 mins prior to substrate addition measured up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396036(CHEMBL2169980)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396039(CHEMBL2169977)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human 5HT2c receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium influx measured up to 30 secs by aequorin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396034(TCMDC-139046 | CHEMBL586213)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2C19 using 3-butyryl-7-methoxycoumarin as substrate incubated for 30 mins prior to substrate addition measured up to 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50396034(TCMDC-139046 | CHEMBL586213)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxyquinoline as substrate incubated for 30 mins prior to substrate addition measured up to 10 mins by fluori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed