Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50039585
LigandPNGBDBM50380371(CHEMBL2017970)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380366(CHEMBL2017965)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380369(CHEMBL2017968)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380367(CHEMBL2017966)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380370(CHEMBL2017969)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380372(CHEMBL2016592)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380377(CHEMBL2017977 | WO2007/084786, Compound 85)
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380376(CHEMBL2017976)
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380365(CHEMBL2017971)
Affinity DataIC50: 18.4nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380368(CHEMBL2017967)
Affinity DataIC50: 21nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380375(CHEMBL2017975)
Affinity DataIC50: 23nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 30nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380373(CHEMBL2017972)
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 52nMAssay Description:Inhibition of PI3K p110alpha subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380374(CHEMBL2017973)
Affinity DataIC50: 68nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50336868(N-(6-(6-aminopyridin-3-yl)-2-morpholinopyrimidin-4...)
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 116nMAssay Description:Inhibition of PI3K p110delta subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380364(CHEMBL2017978)
Affinity DataIC50: 142nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 166nMAssay Description:Inhibition of PI3K p110beta subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 262nMAssay Description:Inhibition of PI3K p110gamma subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PI3K VPS34 using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of mTOR after 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PI4Kbeta using 1-alpha-phosphatidylinositol as substrate by ATP depletion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed