Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50045079
TargetBeta-casein(Bovine)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: >1nMAssay Description:Binding affinity to bovine beta-casein A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: >1nMAssay Description:Binding affinity to induced myeloid leukemia cell differentiation protein 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetBcl-2-like protein 10 [11-204](Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: >1nMAssay Description:Binding affinity to Bcl-b (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044472(CHEMBL3313966)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM27078(N-[3-(1H-1,3-benzodiazol-2-yl)-1H-pyrazol-4-yl]ben...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetGlutathione S-transferase Mu 1(Mouse)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044547(CHEMBL3314090)
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse GSTM1-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM27078(N-[3-(1H-1,3-benzodiazol-2-yl)-1H-pyrazol-4-yl]ben...)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36511(CID46398842 | 5-((2-Carboxy-1H-benzo[g]indol-1-yl)...)
Affinity DataIC50: 80nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044550(CHEMBL3314097)
Affinity DataKd:  200nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36510(CID46398840 | 1-(Carboxymethyl)-1H-benzo[g]indole-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAurora kinase A(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM24637(2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole | JMC52379...)
Affinity DataIC50: 910nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50060582(Decamethonium Iodide | decane-1,10-bis(trimethylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 1(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM24637(2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole | JMC52379...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36501(CID68686 | 2-(5-chloro-3-methylbenzo[b]thiophen-2-...)
Affinity DataIC50: 5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36500(CID205058 | 2-(5-Chlorobenzo[b]thiophen-3-yl)aceti...)
Affinity DataIC50: 5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36502(CID736818 | 2-(6-Methoxybenzofuran-3-yl)acetic aci...)
Affinity DataIC50: 5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36503(CID6932064 | (S)-1-((Benzyloxy)carbonyl)indoline-2...)
Affinity DataIC50: 5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044549(CHEMBL3314093)
Affinity DataKd:  0nMAssay Description:Binding affinity to acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044548(CHEMBL3314092)
Affinity DataKd:  0nMAssay Description:Binding affinity to acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0nMAssay Description:Binding affinity to acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed