Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50044451
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50227631(2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...)
Affinity DataIC50: 3nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017559(CHEMBL3288316)
Affinity DataIC50: 60nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017562(CHEMBL3288319)
Affinity DataIC50: 150nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017560(CHEMBL3288317)
Affinity DataIC50: 240nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017558(CHEMBL3288315)
Affinity DataIC50: 250nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017556(CHEMBL3288313)
Affinity DataIC50: 600nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017561(CHEMBL3288318)
Affinity DataIC50: 700nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017556(CHEMBL3288313)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017552(CHEMBL3288309)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017531(CHEMBL3288308)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017552(CHEMBL3288309)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017516(CHEMBL3288307)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017560(CHEMBL3288317)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017553(CHEMBL3288310)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017564(CHEMBL3288321)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017553(CHEMBL3288310)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017554(CHEMBL3288311)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017516(CHEMBL3288307)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017555(CHEMBL3288312)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017564(CHEMBL3288321)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017563(CHEMBL3288320)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017531(CHEMBL3288308)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017561(CHEMBL3288318)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017559(CHEMBL3288316)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017558(CHEMBL3288315)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017557(CHEMBL3288314)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017562(CHEMBL3288319)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017554(CHEMBL3288311)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of microsomal PGES-1 (unknown origin) assessed as PGH2 conversion to PGE2 after 1 min by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017555(CHEMBL3288312)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017557(CHEMBL3288314)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50017563(CHEMBL3288320)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured as H2DCFDA conversion to 2',7'-dichlorofluorescein preincubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed