Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50044356
TargetInterferon alpha/beta receptor 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014088(CHEMBL1617534 | DNDI1417107)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to IFNAR (unknown origin) assessed as inhibition of interaction with IFN-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetElongin-C(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50446134(CHEMBL3108877)
Affinity DataKd:  1.00E+7nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from VHL/elongins-B/elonginC (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetElongin-C(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014097(CHEMBL3260851)
Affinity DataIC50: 900nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from VHL/elongins-B/elonginC (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetElongin-C(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50446138(CHEMBL3108881)
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from 6xHis-tagged VHL (1 to 213)/elongins-B/elonginC (unknown origin) expressed in Escherichia coli BL21 after 1 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
LigandPNGBDBM50014095(CHEMBL3260850)
Affinity DataIC50: 1.17E+5nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from 6xHis-tagged VHL (1 to 213)/elongins-B/elonginC (unknown origin) expressed in Escherichia coli BL21 after 1 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014089(CHEMBL1236726)
Affinity DataKi:  109nMAssay Description:Displacement of fluorescent P4 peptide from recombinant human MDM2 (18 to 125) expressed in Escherichia coli BL21(DE3) RIL expression system after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014093(CHEMBL3260848)
Affinity DataKi:  250nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014092(CHEMBL3259830 | US9187441, 9l)
Affinity DataKi:  400nMAssay Description:Displacement of fluorescent P4 peptide from MDM2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014094(CHEMBL3260849)
Affinity DataKi:  600nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  916nMAssay Description:Displacement of fluorescent P4 peptide from recombinant human MDM2 (18 to 125) expressed in Escherichia coli BL21(DE3) RIL expression system after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014090(CHEMBL3260846)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of fluorescent P4 peptide from recombinant human MDM2 (18 to 125) expressed in Escherichia coli BL21(DE3) RIL expression system after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTranscription factor 7-like 2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014098(CHEMBL3260852)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of beta-catenin/T cell factor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCatenin beta-1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014148(CHEMBL3260853)
Affinity DataKi:  1.36E+3nMAssay Description:Competitive binding affinity to human beta-catenin (142 to 686) assessed as inhibition of C-terminally fluorescein-labeled Tcf4 interaction after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014091(CHEMBL3260847)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of fluorescent P4 peptide from MDM2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCatenin beta-1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50014132(CHEMBL2323032)
Affinity DataKi:  3.14E+3nMAssay Description:Competitive binding affinity to human beta-catenin (142 to 686) assessed as inhibition of C-terminally fluorescein-labeled Tcf4 interaction after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed