Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 6339
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM50324514((+)-Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7...)
Affinity DataIC50: 0.700nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM50228397(CHEMBL237067 (9) | CHEMBL237067 | 8-((S)-3-amino-p...)
Affinity DataIC50: 3nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123776((2S)-1-(2-{[(1r,3s,5R,7S)-3-hydroxyadamantan-1- yl...)
Affinity DataIC50: 3.5nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123777((2S,3S)-2-amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3...)
Affinity DataIC50: 6nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123775(2-(3-aminopiperidin-1-yl)-3-(but-2-yn-1-yl)-7- met...)
Affinity DataIC50: 7nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM50333184(5-(aminomethyl)-6-isobutyl-2-methyl-4-p-tolylnicot...)
Affinity DataIC50: 18nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 18nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM50212927(CHEMBL233360 | CHEMBL233360 (15) | (1S,2R,5S)-5-[3...)
Affinity DataIC50: 21nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 22nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM50210657(CHEMBL235120 (16) | CHEMBL235120 | (R)-3-amino-4-(...)
Affinity DataIC50: 23nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123778((3R)-1-{[1,2,4]triazolo[4,3-a]pyrimidin-7-yl}-4- (...)
Affinity DataIC50: 26nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123779((2R)-2-[4-({2-[(2S)-1-[(3R)-3-amino-4-(5-fluoro-2-...)
Affinity DataIC50: 33nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123774(2-((2-(6,7-Dimethoxy-3,4- dihydroisoquinolin-2(1H)...)
Affinity DataIC50: 78nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123773(N-(2,4-Dichlorophenyl)-2-((2-(6,7- dimethoxy-3,4-d...)
Affinity DataIC50: 92nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123772(N-(4-Cyanophenyl)-2-((2-(6,7-dimethoxy- 3,4-dihydr...)
Affinity DataIC50: 133nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123768(2-((2-(6,7-Dimethoxy-3,4- dihydroisoquinolin-2(1H)...)
Affinity DataIC50: 148nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123770(N-(4-Chlorophenyl)-2-((2-(6,7-dimethoxy- 3,4-dihyd...)
Affinity DataIC50: 156nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123767(2-((2-(6,7-Dimethoxy-3,4- dihydroisoquinolin-2(1H)...)
Affinity DataIC50: 178nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123766(N-(2,4-Dichlorophenyl)-2-((2-(6,7- dimethoxy-3,4-d...)
Affinity DataIC50: 182nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123769(2-((2-(6,7-Dimethoxy-3,4- dihydroisoquinolin-2(1H)...)
Affinity DataIC50: 226nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123780(CHEMBL1808475 | 2-{[3-(aminomethyl)-2-(2-methylpro...)
Affinity DataIC50: 240nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123771(N-(3-Chloro-4-fluorophenyl)-2-((2-(6,7- dimethoxy-...)
Affinity DataIC50: 245nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123763(N-(4-Chlorophenyl)-2-((2-(6,7-dimethoxy- 3,4-dihyd...)
Affinity DataIC50: 267nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123761(2-((2-(6,7-Dimethoxy-3,4- dihydroisoquinolin-2(1H)...)
Affinity DataIC50: 271nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM15463(4-[(3R)-3-[(2-oxo-2-phenylethyl)amino]butyl]benzam...)
Affinity DataIC50: 280nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123764(N-(3-Chloro-4-fluorophenyl)-2-((2-(6,7- dimethoxy-...)
Affinity DataIC50: 298nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123781(CHEMBL1812901 | 3-(aminomethyl)-2-(2-methylpropyl)...)
Affinity DataIC50: 360nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123762(2-((2-(6,7-Dimethoxy-3,4- dihydroisoquinolin-2(1H)...)
Affinity DataIC50: 387nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123782((2S,3S)-2-amino-3-(4-chloro-2-fluorophenyl)-1- [(3...)
Affinity DataIC50: 480nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123765(N-(4-Cyanophenyl)-2-((2-(6,7-dimethoxy- 3,4-dihydr...)
Affinity DataIC50: 494nMpH: 7.5Assay Description:The reaction contained 10 uM of Ala-Pro-AMC, 50 pM of enzyme DDP-4, different concentrations of test compounds, and assay buffer (100 mM HEPES, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123783(1-{2-[(1-hydroxy-2-methylpropan-2- yl)amino]acetyl...)
Affinity DataIC50: 1.11E+3nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM50151805(CHEMBL184262 (24) | CHEMBL184262 | (R)-3-Amino-4-p...)
Affinity DataIC50: 3.00E+3nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123784((2S)-2-[4-({[(2S)-1-[(2S)-2-amino-2- cyclohexylace...)
Affinity DataIC50: 7.20E+3nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM50350563(CHEMBL1812728 | CHEMBL1812728 (26))
Affinity DataIC50: 1.60E+4nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

LigandPNGBDBM123785((2S,3S)-2-amino-3-[4-fluoro-2- (trifluoromethyl)ph...)
Affinity DataIC50: 5.40E+4nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed