Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50044077
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437049(CHEMBL2403355)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001015(CHEMBL2403357)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001003(CHEMBL3235686)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50437050(CHEMBL2403349)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001005(CHEMBL3235682)
Affinity DataIC50: 88nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells assessed as conversion of [3H]E1S to [3H]E1 and [3H]E2 after 5 hrs by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001001(CHEMBL3235685)
Affinity DataIC50: 115nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001002(CHEMBL1782331 | 3,3-Bis(4-Hydroxyphenyl)Pentane | ...)
Affinity DataIC50: 118nMAssay Description:Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001014(CHEMBL3235689)
Affinity DataIC50: 170nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells assessed as conversion of [3H]E1S to [3H]E1 and [3H]E2 after 5 hrs by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001003(CHEMBL3235686)
Affinity DataIC50: 804nMAssay Description:Antagonist activity at human Gal4-fused ER-beta expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50001004(CHEMBL3235681)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells assessed as conversion of [3H]E1S to [3H]E1 and [3H]E2 after 5 hrs by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed