Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50044174
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461(4,4'-(ethene-1,2-diyl)dibenzimidamide | 4-((E)-2-{...)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461(4,4'-(ethene-1,2-diyl)dibenzimidamide | 4-((E)-2-{...)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50: 1.66E+5nMAssay Description:Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461(4,4'-(ethene-1,2-diyl)dibenzimidamide | 4-((E)-2-{...)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50: 1.86E+5nMAssay Description:Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50: 2.83E+5nMAssay Description:Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461(4,4'-(ethene-1,2-diyl)dibenzimidamide | 4-((E)-2-{...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed