Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50043906
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448225(CHEMBL3120824)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448224(CHEMBL3120825)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448235(CHEMBL3120758)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448221(CHEMBL3120828)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448229(CHEMBL3120820)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448230(CHEMBL3120819)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448231(CHEMBL3120818)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448232(CHEMBL3120817)
Affinity DataIC50: 1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448226(CHEMBL3120823)
Affinity DataIC50: 2nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448223(CHEMBL3120826)
Affinity DataIC50: 2nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448222(CHEMBL3120827)
Affinity DataIC50: 2nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448227(CHEMBL3120822)
Affinity DataIC50: 2nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448237(CHEMBL3120755)
Affinity DataIC50: 4nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448238(CHEMBL3120754)
Affinity DataIC50: 4nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448228(CHEMBL3120821)
Affinity DataIC50: 7nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50319665(AMG-221 | (S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2...)
Affinity DataIC50: 7nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448231(CHEMBL3120818)
Affinity DataIC50: 9nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448229(CHEMBL3120820)
Affinity DataIC50: 9nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448232(CHEMBL3120817)
Affinity DataIC50: 10nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448233(CHEMBL3120816)
Affinity DataIC50: 12nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448235(CHEMBL3120758)
Affinity DataIC50: 12nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448227(CHEMBL3120822)
Affinity DataIC50: 16nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448223(CHEMBL3120826)
Affinity DataIC50: 21nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448230(CHEMBL3120819)
Affinity DataIC50: 22nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448221(CHEMBL3120828)
Affinity DataIC50: 24nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448222(CHEMBL3120827)
Affinity DataIC50: 28nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448225(CHEMBL3120824)
Affinity DataIC50: 28nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448224(CHEMBL3120825)
Affinity DataIC50: 46nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448240(CHEMBL3120761)
Affinity DataIC50: 53nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448234(CHEMBL3120759)
Affinity DataIC50: 54nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448236(CHEMBL3120756)
Affinity DataIC50: 57nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448237(CHEMBL3120755)
Affinity DataIC50: 70nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448239(CHEMBL3120753)
Affinity DataIC50: 80nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448241(CHEMBL3120760)
Affinity DataIC50: 89nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448233(CHEMBL3120816)
Affinity DataIC50: 94nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448228(CHEMBL3120821)
Affinity DataIC50: 99nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448238(CHEMBL3120754)
Affinity DataIC50: 113nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448243(CHEMBL3120752)
Affinity DataIC50: 190nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448226(CHEMBL3120823)
Affinity DataIC50: 196nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448244(CHEMBL3120751)
Affinity DataIC50: 390nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50319665(AMG-221 | (S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2...)
Affinity DataIC50: 470nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448239(CHEMBL3120753)
Affinity DataIC50: 640nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448242(CHEMBL3120757)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448234(CHEMBL3120759)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448236(CHEMBL3120756)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed