Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50043817
TargetPoly [ADP-ribose] polymerase 1(Human)
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446668(CHEMBL3113568)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446671(CHEMBL3113565)
Affinity DataIC50: 11nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446667(CHEMBL3113569)
Affinity DataIC50: 19nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446666(CHEMBL3113570)
Affinity DataIC50: 22nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446670(CHEMBL3113566)
Affinity DataIC50: 26nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446669(CHEMBL3113567)
Affinity DataIC50: 30nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Washington University Saint Louis

Curated by ChEMBL
LigandPNGBDBM27497(2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...)
Affinity DataIC50: 170nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)