Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50043952
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of full length human SGLT2 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 1.5 hrs by cell-based topcount scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 540nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 820nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 900nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50308469(CHEMBL589305 | CHEMBL3125314 | CHEMBL3125459 | CHE...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50448923(CHEMBL3125455 | CHEMBL3125318 | CHEMBL3125456 | CH...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human SGLT1 assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs by cell-based topcount scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed