Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50022558
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 0.950nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 4.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 5.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 5.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 6.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 8.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 9.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Yes(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase FRK(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 54nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEphrin type-A receptor 6(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 54nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEphrin type-B receptor 4(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 68nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 86nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Yes(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 163nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 413nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM209865(ASP-3026 | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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