Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50043844
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447157BDBM50447157(CHEMBL3112595)
Affinity DataIC50: 38nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 60nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447174BDBM50447174(CHEMBL3113129)
Affinity DataIC50: 160nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447170BDBM50447170(CHEMBL3113136)
Affinity DataIC50: 170nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447172BDBM50447172(CHEMBL3113134)
Affinity DataIC50: 220nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447164BDBM50447164(CHEMBL3113143)
Affinity DataIC50: 370nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447173BDBM50447173(CHEMBL3113130)
Affinity DataIC50: 470nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447162BDBM50447162(CHEMBL3113145)
Affinity DataIC50: 480nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447166BDBM50447166(CHEMBL3113141)
Affinity DataIC50: 640nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447159BDBM50447159(CHEMBL3113149)
Affinity DataIC50: 650nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447167BDBM50447167(CHEMBL3113140)
Affinity DataIC50: 740nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447165BDBM50447165(CHEMBL3113142)
Affinity DataIC50: 740nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447158BDBM50447158(CHEMBL3113150)
Affinity DataIC50: 820nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447157BDBM50447157(CHEMBL3112595)
Affinity DataIC50: 880nMAssay Description:Inhibition of BRAF1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447163BDBM50447163(CHEMBL3113144)
Affinity DataIC50: 900nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447161BDBM50447161(CHEMBL3113146)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447168BDBM50447168(CHEMBL3113139)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447169BDBM50447169(CHEMBL3113137)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447160BDBM50447160(CHEMBL3113148)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447171BDBM50447171(CHEMBL3113135)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15211BDBM15211(CHEMBL104264 | H89 | N-(2-{[(2E)-3-(4-bromophenyl)...)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed