Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50005932
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataEC50:  40nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  677nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  786nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359499(METHAMPHETAMINE | (S)Methamphetamine)
Affinity DataEC50:  2.04E+3nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  843nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataEC50:  47nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  126nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  330nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  105nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  34nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  85nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  121nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359499(METHAMPHETAMINE | (S)Methamphetamine)
Affinity DataEC50:  1.82E+3nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359499(METHAMPHETAMINE | (S)Methamphetamine)
Affinity DataEC50:  133nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  1.11E+3nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  56nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  233nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359499(METHAMPHETAMINE | (S)Methamphetamine)
Affinity DataEC50:  279nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataEC50:  261nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  214nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  4nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359499(METHAMPHETAMINE | (S)Methamphetamine)
Affinity DataEC50:  18nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataEC50:  171nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  14nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359499(METHAMPHETAMINE | (S)Methamphetamine)
Affinity DataEC50:  202nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataEC50:  59nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  219nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  170nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM10758(14C-phenylethylamine | 2-phenylethan-1-amine | CHE...)
Affinity DataEC50:  189nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed